Telangiectatic osteosarcoma of the thoracic vertebra: a case report and literature review

Telangiectatic osteosarcoma (TOS) is a rare high-grade malignant tumour found primarily in the metaphysis of long bones, but can also occur in the pelvis, spine and skull. Characterized by extensive vascular dilatation and aggressive behavior, TOS often has a poor prognosis and may be misdiagnosed due to similarities with other lesions. This report presents a case of TOS of the thoracic vertebrae and reviews the relevant literature to enhance clinical awareness. A 44-year-old woman presented with chest and back pain of worsening over two months, accompanied by lower limb numbness and incomplete paralysis. Initial treatment for "low back pain" proved ineffective. Imaging showed osteolytic destruction at T10, which led to surgery, and the tumour was classified as Tomita type III. The tumour was surgically resected, showing vascular proliferation and malignant stromal cells, confirming the pathological diagnosis of TOS. However, she developed complications requiring further surgery for recurrent problems, where a hematoma was discovered. Despite interventions, the patient's condition deteriorated, leading to the diagnosis of pulmonary metastasis and eventual death three months after the second surgery. This case highlights the need for increased awareness and accurate diagnosis of TOS, particularly in atypical presentations.

Authors

Institutions

Publication Details

Journal
Frontiers in Oncology
Published
2025-04-17
DOI
https://doi.org/10.3389/fonc.2025.1537611
Citations
1
Primary Topic
Bone Tumor Diagnosis and Treatments
Type
article
Field-Weighted Citation Impact
1.67

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Telangiectatic osteosarcoma of the thoracic vertebra: a case report and literature review

Xue Wen, Guoquan Li, Wujun Xing, Chenjian Wang et al.
1 citations
Frontiers in Oncology
Bone Tumor Diagnosis and Treatments
1.67
article

Telangiectatic osteosarcoma of the thoracic vertebra: a case report and literature review

Xue Wen, Guoquan Li, Wujun Xing, Chenjian Wang, Kai Zhang, Chen Wang, Qilong Wang, Zhou Yi, Fujun Gou, Xi-Rong Fan
article en
1 citations

Abstract

Telangiectatic osteosarcoma (TOS) is a rare high-grade malignant tumour found primarily in the metaphysis of long bones, but can also occur in the pelvis, spine and skull. Characterized by extensive vascular dilatation and aggressive behavior, TOS often has a poor prognosis and may be misdiagnosed due to similarities with other lesions. This report presents a case of TOS of the thoracic vertebrae and reviews the relevant literature to enhance clinical awareness. A 44-year-old woman presented with chest and back pain of worsening over two months, accompanied by lower limb numbness and incomplete paralysis. Initial treatment for "low back pain" proved ineffective. Imaging showed osteolytic destruction at T10, which led to surgery, and the tumour was classified as Tomita type III. The tumour was surgically resected, showing vascular proliferation and malignant stromal cells, confirming the pathological diagnosis of TOS. However, she developed complications requiring further surgery for recurrent problems, where a hematoma was discovered. Despite interventions, the patient's condition deteriorated, leading to the diagnosis of pulmonary metastasis and eventual death three months after the second surgery. This case highlights the need for increased awareness and accurate diagnosis of TOS, particularly in atypical presentations.

Frontiers in OncologyVol. 15
Gansu University of Traditional Chinese Medicine (CN), Gansu Provincial Hospital (CN)
Natural Science Foundation of Gansu Province
Openalex Percentile: Top 18%
Bone Tumor Diagnosis and Treatments
1.67
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.