Concomitant autoimmunity and late cancers in adult-onset immunodeficiency due to neutralizing anti-IFN-γ autoantibodies
Adult-onset immunodeficiency due to nAIGA is a syndrome associated with concomitant autoimmunity. Chronic infection and autoimmune-mediated inflammation may foster neoplastic changes, but the underlying mechanism is still undetermined. Autoimmune disease and cancer surveillance for patients with nAIGA is advised.
Authors
- Chiao‐Feng Cheng (ORCID: https://orcid.org/0000-0002-8618-9945)
- Ming‐Fu Chang (ORCID: https://orcid.org/0000-0001-7062-3578)
- Bei‐Chia Guo
- Jann‐Tay Wang (ORCID: https://orcid.org/0000-0002-0924-3469)
- Un‐In Wu (ORCID: https://orcid.org/0000-0001-8182-6071)
- Hsin‐Yun Sun (ORCID: https://orcid.org/0000-0003-0074-7721)
- Wang‐Huei Sheng (ORCID: https://orcid.org/0000-0002-5605-7853)
- Yee‐Chun Chen (ORCID: https://orcid.org/0000-0002-1816-9010)
- Yihua Pan (ORCID: https://orcid.org/0000-0001-8274-4019)
- Chih-Yun Cheng
- Aristine Cheng (ORCID: https://orcid.org/0000-0002-1182-7375)
- Wan-Ting Tsai
- Ying‐Chieh Chiang
Institutions
- Taipei City Hospital (TW)
- National Taiwan University Hospital (TW)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-04-17
- DOI
- https://doi.org/10.3389/fimmu.2025.1526439
- Citations
- 3
- Primary Topic
- Immunodeficiency and Autoimmune Disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.39
Funders
- Ministry of Science and Technology, Taiwan
- National Taiwan University Hospital
- National Taiwan University
- National Science and Technology Council