Comprehensive molecular analyses of an autoimmune-related gene predictive model and immune infiltrations using machine learning methods in intracranial aneurysma

The results of bioinformatics analysis in our study elucidated the mechanism of intracranial aneurysm (IA), identifying two key differential genes. Our research highlights the significant roles of immune infiltration and the regulatory networks between genes, miRNAs, and drugs in IA. These findings not only enhance our understanding of the pathogenesis of IA but also suggest potential new avenues for its treatment.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-04-17
DOI
https://doi.org/10.3389/fimmu.2025.1531930
Citations
1
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
Field-Weighted Citation Impact
0.84
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article

Comprehensive molecular analyses of an autoimmune-related gene predictive model and immune infiltrations using machine learning methods in intracranial aneurysma

Yuying Zhao, Zhuobo Zhang, Minxue Zhang, Zhan Liu et al.
1 citations
Frontiers in Immunology
Neuroinflammation and Neurodegeneration Mechanisms
0.84
article

Comprehensive molecular analyses of an autoimmune-related gene predictive model and immune infiltrations using machine learning methods in intracranial aneurysma

Yuying Zhao, Zhuobo Zhang, Minxue Zhang, Zhan Liu, Ling Zhou, Yanling Wang
article en
1 citations

Abstract

The results of bioinformatics analysis in our study elucidated the mechanism of intracranial aneurysm (IA), identifying two key differential genes. Our research highlights the significant roles of immune infiltration and the regulatory networks between genes, miRNAs, and drugs in IA. These findings not only enhance our understanding of the pathogenesis of IA but also suggest potential new avenues for its treatment.

Frontiers in ImmunologyVol. 16
Harbin Medical University (CN), Fourth Affiliated Hospital of Harbin Medical University (CN)
Openalex Percentile: Top 27%
Neuroinflammation and Neurodegeneration Mechanisms
0.84
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