The impact of blood pressure targets on venous return physiology during post cardiac arrest care
This post-hoc analysis of the BOX trial explores VR physiology and how it is influenced by the use of various doses of noradrenaline and dopamine. A higher blood pressure target appears to increase VR by increasing the stressed intravascular volume. This results in an increase in the CO. These findings are important given the worry about the effect of a higher afterload on cardiac function.
Authors
- Rasmus Paulin Beske (ORCID: https://orcid.org/0000-0002-5880-3733)
- Christian Hassager (ORCID: https://orcid.org/0000-0002-1199-0981)
- Jesper Kjærgaard (ORCID: https://orcid.org/0000-0001-5244-0399)
- Johannes Grand (ORCID: https://orcid.org/0000-0002-5511-4668)
- Henrik Schmidt (ORCID: https://orcid.org/0000-0003-1080-3344)
- Anders Åneman (ORCID: https://orcid.org/0000-0003-2096-5304)
- Jacob Eifer Møller (ORCID: https://orcid.org/0000-0003-2873-5845)
- Simon Schneekloth (ORCID: https://orcid.org/0009-0000-2786-3736)
Institutions
- University of Southern Denmark (DK)
- Liverpool Hospital (AU)
- Odense University Hospital (DK)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- UNSW Sydney (AU)
- Ingham Institute (AU)
- South Western Sydney Local Health District (AU)
- Macquarie University (AU)
Publication Details
- Journal
- Acta Anaesthesiologica Scandinavica
- Published
- 2025-04-16
- DOI
- https://doi.org/10.1111/aas.70038
- Citations
- 1
- Primary Topic
- Cardiac Arrest and Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 2.25
Funders
- Hjerteforeningen
- Lundbeckfonden
- Novo Nordisk
- Novo Nordisk Fonden
- Grosserer L. F. Foghts Fond
- H. Lundbeck A/S