Studies on the changes in rectal permeability and intestinal microbiota with developmental age in young rats
This study demonstrates that age-dependent maturation of the rectal barrier is closely linked to microbiota composition and tight junction protein expression, providing insights into developmental mechanisms and potential strategies for pediatric rectal drug delivery.
Authors
- Yunfeng Luo (ORCID: https://orcid.org/0000-0003-1490-9293)
- Guosong Zhang (ORCID: https://orcid.org/0000-0002-4514-437X)
- Laixin Luo (ORCID: https://orcid.org/0000-0002-6543-6011)
- Qian Liu (ORCID: https://orcid.org/0000-0002-1005-8615)
- Xia Mao (ORCID: https://orcid.org/0000-0002-9747-3642)
Institutions
- Jiangxi University of Traditional Chinese Medicine (CN)
- Gansu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-04-17
- DOI
- https://doi.org/10.3389/fmicb.2025.1551693
- Citations
- 2
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- Education Department of Jiangxi Province