Association of HLA Mismatch With Adverse Cardiovascular Events Following Lung Transplantation: A Single‐Center Study

In this study cohort, high HLA mismatch and HLA-DQ mismatch were not associated with increased adverse cardiovascular events. Furthermore, neither transplant rejection nor CMV infection increased the risk for cardiovascular events. The high cardiovascular event rates following LuTx necessitate meticulous cardiovascular follow-up, irrespective of immunological matching.

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Publication Details

Journal
Clinical Transplantation
Published
2025-04-01
DOI
https://doi.org/10.1111/ctr.70157
Primary Topic
Transplantation: Methods and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Association of HLA Mismatch With Adverse Cardiovascular Events Following Lung Transplantation: A Single‐Center Study

Christian M. Hagl, Steffen Maßberg, Jürgen Behr, Christian Schneider et al.
3 links
Clinical Transplantation
Transplantation: Methods and Outcomes
article

Association of HLA Mismatch With Adverse Cardiovascular Events Following Lung Transplantation: A Single‐Center Study

Christian M. Hagl, Steffen Maßberg, Jürgen Behr, Christian Schneider, Roland Tomasi, M Scherzer, Enzo Lüsebrink, Tobias Veit, Katrin Milger, Michael Irlbeck, Carlo Mümmler, Andrea Dick, Nikolaus Kneidinger, Sebastian Michel, Daniel Roden, Michael Gerckens, Julia Höpler, Leonhard Binzenhöfer, Rudolf Hatz, Hugo Lanz, Teresa Kauke, Nils Gade, Sabine Hoffmann, Paula Seifert
article en

Abstract

In this study cohort, high HLA mismatch and HLA-DQ mismatch were not associated with increased adverse cardiovascular events. Furthermore, neither transplant rejection nor CMV infection increased the risk for cardiovascular events. The high cardiovascular event rates following LuTx necessitate meticulous cardiovascular follow-up, irrespective of immunological matching.

Clinical TransplantationVol. 39(4)
Medical University of Graz (AT), University Hospital Bonn (DE), LMU Klinikum (DE), München Klinik (DE), German Centre for Cardiovascular Research (DE), German Center for Lung Research (DE), Ludwig-Maximilians-Universität München (DE)
Good health and well-being
Openalex Percentile: Top 86%
Transplantation: Methods and Outcomes
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