An approximate method to find a hemodynamic significance of a severe larger coronary artery pathologic tortuosity

A developed approximate method allows cardiologists with acceptable accuracy and speed to determine quantitative changes in blood flow characteristics in large coronary arteries caused by the appearance of their pathological tortuosity, as well as to establish the hemodynamic significance of these changes based only on the corresponding coronary angiography. The proposed approach is based on replacing the blood flow in the initially normal and later pathologically reported artery with the corresponding averaged flows, further finding the desired characteristics of the studied flows through the attributes of the corresponding averaged flows and comparative analysis of the determined characteristics. This non-invasive method allows one to exclude from consideration many similar factors for initially normal and later pathologically reported areas of the studied artery, making it possible to determine the desired blood flow characteristics at any time after coronary angiography. It is not related to solving complex technical problems. It does not require special equipment and professional training, or great financial and time costs. The method passed a successful experimental test, after which it was recommended by cardiologists for clinical use. As a result of its application, a general connection of the hemodynamic significance of pathological tortuosity with some curls was revealed. A strong correlation was established between the main geometric and hemodynamic characteristics of development and the basic clinical indicators of the corresponding diseases. This allows us to talk about the independent influence of the pathology of the development of large coronary arteries on the symptomatic picture. Another result of the clinical application of this method was the determination of critical parameters for the majority of curls, the relative volume reduction of blood flow, and the frequency of angina attacks, starting from which the pathological survival of a large coronary artery can be hemodynamically significant. The obtained results and their analysis form the basis for further successful clinical application of the developed method.