Unraveling the oncogenic role of LINC00504 and its interaction with miR-545-3p and ARIHI in hepatocellular carcinoma: novel insights for molecular therapy

This study uncovers the significant tumor-suppressing role of LINC00504 in HCC, potentially through a mechanism involving the targeting of miR-545-3p, which in turn inhibits the ARIH1. These findings offer new potential targets for HCC molecular treatment.

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Publication Details

Journal
Discover Oncology
Published
2025-04-17
DOI
https://doi.org/10.1007/s12672-025-02328-2
Primary Topic
Cancer-related molecular mechanisms research
Type
article
Field-Weighted Citation Impact
0.00
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article

Unraveling the oncogenic role of LINC00504 and its interaction with miR-545-3p and ARIHI in hepatocellular carcinoma: novel insights for molecular therapy

Eugene Ke, Kai Yang, Qin Zhang, Hai Zhang et al.
Discover Oncology
Cancer-related molecular mechanisms research
article

Unraveling the oncogenic role of LINC00504 and its interaction with miR-545-3p and ARIHI in hepatocellular carcinoma: novel insights for molecular therapy

Eugene Ke, Kai Yang, Qin Zhang, Hai Zhang, Junhua Wang, Zhiyong Hu, Cheng Luo
article en

Abstract

This study uncovers the significant tumor-suppressing role of LINC00504 in HCC, potentially through a mechanism involving the targeting of miR-545-3p, which in turn inhibits the ARIH1. These findings offer new potential targets for HCC molecular treatment.

Discover OncologyVol. 16(1)
Huangshi Central Hospital (CN)
Openalex Percentile: Top 91%
Cancer-related molecular mechanisms research
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