Transcriptomic analysis reveals distinct molecular signatures and regulatory networks of osteoarthritic chondrocytes versus mesenchymal stem cells during chondrogenesis
Our results identified significant genes involved in chondrogenesis. These findings provide new avenues for exploring the genetic mechanism underlying cartilage synthesis and novel targets for preclinical intervention and clinical treatment.
Authors
- Viraj Krishna Mishra
- Navneet Kumar Dubey (ORCID: https://orcid.org/0000-0002-3540-5281)
- Tsung-Yu Lin (ORCID: https://orcid.org/0000-0002-4755-2545)
- Lung‐Wen Tsai (ORCID: https://orcid.org/0000-0002-3541-5834)
- TP Chaturvedi (ORCID: https://orcid.org/0000-0002-8574-9779)
- Sachin Narayan (ORCID: https://orcid.org/0000-0002-0787-1349)
- Rajni Dubey
- Hsu-Wei Fang (ORCID: https://orcid.org/0000-0001-8931-8434)
Institutions
- National Taipei University of Technology (TW)
- Taipei Medical University Hospital (TW)
- Mackay Junior College of Medicine, Nursing and Management (TW)
- Taipei Medical University (TW)
Publication Details
- Journal
- Biomedical Papers
- Published
- 2025-04-17
- DOI
- https://doi.org/10.5507/bp.2025.008
- Citations
- 1
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.67