Analysis of Pathogenesis and Mechanism of Rabies

Given the global impact of rabies virus and its universally fatal outcome post-infection, it is imperative for society to prioritize the elucidation of its pathogenesis and implement effective measures to control its infection rate. This paper presents an in-depth analysis of the pathogenesis of rabies and discuss the specific mechanism of action. It describes the invasion of the virus through saliva, the reverse transport of the virus to the center in the nerve, causing pathological damage and clinical symptoms, and discusses the host immunity and virus escape, as well as the peripheral spread of the virus. Finally, it summarizes the current situation and prospects the future research direction. In the future, it is necessary to conduct in-depth analysis of the molecular mechanisms of the interaction between rabies virus and its host, and develop precisely targeted antiviral drugs. Optimizing the vaccines with the help of advanced technologies can be used to enhance the immune effect.

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Publication Details

Journal
Theoretical and Natural Science
Published
2025-04-17
DOI
https://doi.org/10.54254/2753-8818/2025.22169
Primary Topic
Rabies epidemiology and control
Type
article
Field-Weighted Citation Impact
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article

Analysis of Pathogenesis and Mechanism of Rabies

Mulading Muhetaer
Theoretical and Natural Science
Rabies epidemiology and control
article

Analysis of Pathogenesis and Mechanism of Rabies

Mulading Muhetaer
article en

Abstract

Given the global impact of rabies virus and its universally fatal outcome post-infection, it is imperative for society to prioritize the elucidation of its pathogenesis and implement effective measures to control its infection rate. This paper presents an in-depth analysis of the pathogenesis of rabies and discuss the specific mechanism of action. It describes the invasion of the virus through saliva, the reverse transport of the virus to the center in the nerve, causing pathological damage and clinical symptoms, and discusses the host immunity and virus escape, as well as the peripheral spread of the virus. Finally, it summarizes the current situation and prospects the future research direction. In the future, it is necessary to conduct in-depth analysis of the molecular mechanisms of the interaction between rabies virus and its host, and develop precisely targeted antiviral drugs. Optimizing the vaccines with the help of advanced technologies can be used to enhance the immune effect.

Theoretical and Natural ScienceVol. 93(1)
Nanjing Foreign Language School (CN)
Openalex Percentile: Top 91%
Rabies epidemiology and control
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