Phosphatidylcholine and frailty: a Mendelian randomization study and immune mediation
This study provides novel evidence that supports the causal association between PC species and frailty, with the immune system playing a crucial role in this pathway. These findings offer new insights into potential targets for the intervention of frailty in the elderly population.
Authors
- Shunmei Huang (ORCID: https://orcid.org/0000-0003-2997-1073)
- Yunmei Yang (ORCID: https://orcid.org/0000-0002-6646-4954)
- Suisui Luo
- Qin Zhang (ORCID: https://orcid.org/0000-0002-4597-7697)
- Qunhua Han
- Lijun Zhu
Institutions
- Zhejiang Hospital (CN)
- First Affiliated Hospital Zhejiang University (CN)
Publication Details
- Journal
- Archives of Gerontology and Geriatrics
- Published
- 2025-04-17
- DOI
- https://doi.org/10.1016/j.archger.2025.105863
- Citations
- 2
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 2.45
Funders
- National Natural Science Foundation of China