Wild Onion Extraction and It’s Study on Antioxidant and Anthelmintic Property: An In-vitro Assessment

Wild onions are an essential therapeutic herb. In several in vitro models, we studied Wild Onion extracts' phenolic components, antioxidant, anti-hyperglycemic, and anthelmintic properties. Wild onion pieces were extracted using several solvents in ascending order of polarity, including chloroform, ethyl acetate, methanol, ethanol, and distilled water. The antioxidant activity of wild onion extracts was assessed in a variety of in vitro model systems, including DPPH scavenging, ferric-reducing antioxidant power, and metal-chelating capacity. The phenolic content was also evaluated, and finally, an in vitro anthelmintic investigation was conducted out utilizing Phertima posthuma. In vitro studies revealed that several Wild Onion extracts have considerable DPPH Ferric-Reducing Antioxidant Power and Metal-Chelating Capacity scavenging activity. The findings revealed a clear link between phenolic acid concentration and antioxidant activity. The anthelmintic investigation found that the aqueous extract had the highest in-vitro activity, taking 3.52±0.158 min to paralyze and 2.74±0.247 min to kill earthworms. The experimental results gained in the laboratory model may give a foundation for the traditional usage of these pieces as antioxidants and anthelmintics. Our data show that the traditional medicinal claims for this plant, in the near future, will undoubtedly be able to replace the synthetic medications to which there is an increased incidence of drug interactions and resistance.