Different Patterns of Oral Mucositis and Microbiota Injury After Total Body Irradiation- Versus Chemotherapy-Based Myeloablative Allogeneic Hematopoietic Cell Transplantation
We demonstrated different patterns of OM, microbiota injury, and salivary flow rate after TBI- versus chemotherapy-based conditioning. If validated in future studies, our findings could enhance evidence-based pretransplant counseling on oral toxicity and have implications for short- and long-term oral health in transplant survivors.
Authors
- Omar Y. Mian (ORCID: https://orcid.org/0000-0002-8133-8120)
- Maryam Ebadi (ORCID: https://orcid.org/0009-0004-5848-4789)
- Gale Sebastian
- Rania Abasaeed
- Yolanda D. Tseng (ORCID: https://orcid.org/0000-0002-4070-346X)
- Michele Lloid
- Hakan Gem
- David Dean
- Samuel S. Minot (ORCID: https://orcid.org/0000-0003-1639-3905)
- Armin Rashidi (ORCID: https://orcid.org/0000-0002-9384-272X)
Institutions
- Infectious Disease Research Institute (US)
- University of Washington Medical Center (US)
- Fred Hutch Cancer Center (US)
Publication Details
- Journal
- Advances in Radiation Oncology
- Published
- 2025-04-17
- DOI
- https://doi.org/10.1016/j.adro.2025.101787
- Primary Topic
- Oral health in cancer treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Foundation for the National Institutes of Health