Claisen rearrangement enabled efficient access to biaryl phenols
A rapid method for C2-arylation of hydroxypyranone systems <i>via</i> a reductive iodonio-Claisen rearrangement (RICR) of λ<sup>3</sup>-iodanes is reported. By integrating the rearrangement products with a tandem Claisen reaction, a series of otherwise inaccessible biaryl phenols were efficiently synthesized.
Authors
- Shifa Zhu (ORCID: https://orcid.org/0000-0001-5172-7152)
- Tongxiang Cao (ORCID: https://orcid.org/0000-0003-4246-4340)
- Yu Ke (ORCID: https://orcid.org/0000-0001-9854-0360)
Institutions
- South China University of Technology (CN)
Publication Details
- Journal
- Organic & Biomolecular Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5ob00468c
- Primary Topic
- Oxidative Organic Chemistry Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- South China University of Technology
- Guangdong Science and Technology Department