Nicotinamide mononucleotide biosynthesis and the F-actin cytoskeleton regulate spindle assembly and oocyte maturation quality in post-ovulatory aged porcine oocytes
F-actin polymerization through NAD<sup>+</sup> generated from NMN is an essential factor in determining oocyte quality. This effect is mediated by microtubules related to spindle assembly in POA oocytes.
Authors
- Seung‐Bin Yoon (ORCID: https://orcid.org/0000-0002-0056-4995)
- Deog‐Bon Koo (ORCID: https://orcid.org/0000-0001-7825-9598)
- Seul‐Gi Yang (ORCID: https://orcid.org/0000-0003-3247-2443)
- Ji-Su Kim (ORCID: https://orcid.org/0000-0002-6885-0947)
- Hyo‐Jin Park (ORCID: https://orcid.org/0000-0003-3287-2914)
- Ji-Hyun Shin
Institutions
- Korea Research Institute of Bioscience and Biotechnology (KR)
- Korea University of Science and Technology (KR)
- Daegu University (KR)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2025-04-17
- DOI
- https://doi.org/10.1186/s12964-025-02200-4
- Citations
- 4
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 7.51
Funders
- National Research Foundation
- Korea Research Institute of Bioscience and Biotechnology
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea