Can the Early Warning Score (ANDC) Predict Tocilizumab Efficacy in Patients with COVID-19 Cytokine Storm?
Lactate dehydrogenase was identified as an independent predictor of response to tocili- zumab treatment. The ANDC score showed the highest AUC value in steroid-naïve patients before tocilizumab, whereas LDH showed the highest AUC value in patients receiving steroids before tocili- zumab. Both the ANDC score and LDH levels show potential as valuable tools to guide treatment decisions.
Authors
- Özlem Kılıç (ORCID: https://orcid.org/0000-0001-9582-4376)
- Mehmet Nur Kaya (ORCID: https://orcid.org/0000-0003-4368-3078)
- Duygu Tecer (ORCID: https://orcid.org/0000-0002-8816-6181)
- Sedat Yılmaz (ORCID: https://orcid.org/0000-0002-4691-3417)
- Muhammet Çınar (ORCID: https://orcid.org/0000-0002-6150-3539)
Institutions
- Hakkari University (TR)
- Sağlık Bilimleri Üniversitesi (TR)
- University of Health Sciences Antigua (AG)
Publication Details
- Journal
- European Journal of Rheumatology
- Published
- 2025-04-17
- DOI
- https://doi.org/10.5152/eurjrheum.2025.24048
- Citations
- 1
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.40