Bilateral Corneal Copper Deposition in Monoclonal Gammopathy of Undetermined Significance: Diagnostic Insights and Treatment With Descemet Membrane Endothelial Keratoplasty and Descemet Stripping Only

Bilateral corneal copper deposition can be a presenting sign of MGUS, mandating systemic investigation. While DMEK offered temporary improvement although recurrence occurred. DSO shows potential as a therapeutic alternative. Recognizing these ocular findings is critical for timely MGUS diagnosis and monitoring, though optimal corneal treatment requires further research.

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Publication Details

Journal
Cornea
Published
2025-04-16
DOI
https://doi.org/10.1097/ico.0000000000003880
Primary Topic
Ocular Diseases and Behçet’s Syndrome
Type
article
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article

Bilateral Corneal Copper Deposition in Monoclonal Gammopathy of Undetermined Significance: Diagnostic Insights and Treatment With Descemet Membrane Endothelial Keratoplasty and Descemet Stripping Only

M.T. Allende, Ariadna Quer Pi‐Sunyer, Antoni Sabala Llopart, M. Martínez et al.
Cornea
Ocular Diseases and Behçet’s Syndrome
article

Bilateral Corneal Copper Deposition in Monoclonal Gammopathy of Undetermined Significance: Diagnostic Insights and Treatment With Descemet Membrane Endothelial Keratoplasty and Descemet Stripping Only

M.T. Allende, Ariadna Quer Pi‐Sunyer, Antoni Sabala Llopart, M. Martínez, Julia N Widmer-Pintos, Consuelo Arnaldos-López, Sofía del-Pozo-Lérida
article en

Abstract

Bilateral corneal copper deposition can be a presenting sign of MGUS, mandating systemic investigation. While DMEK offered temporary improvement although recurrence occurred. DSO shows potential as a therapeutic alternative. Recognizing these ocular findings is critical for timely MGUS diagnosis and monitoring, though optimal corneal treatment requires further research.

CorneaVol. 44(9)
Hebron University (PS), Hospital General de Granollers (ES), Vall d'Hebron Hospital Universitari (ES), Hospital Universitari Germans Trias i Pujol (ES)
Good health and well-being
Openalex Percentile: Top 86%
Ocular Diseases and Behçet’s Syndrome
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Bilateral Corneal Copper Deposition in Monoclonal Gammopathy of Undetermined Significance: Diagnostic Insights and Treatment With Descemet Membrane Endothelial Keratoplasty and Descemet Stripping Only — M.T. Allende, Ariadna Quer Pi‐Sunyer, et al. · Cornea (2025) | TGRS Research Map | TGRS