Massive Lamotrigine Intoxication Refractory to Sodium Bicarbonate Treatment

The use of ILE as a rescue option, in addition to other supportive measures, and therapeutic drug monitoring seem to be a reasonable approach, given the patient's refractory response to sodium bicarbonate. Continued research and reporting of such cases will help expand the evidence base and refine management strategies for severe LTG intoxication.

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Publication Details

Journal
Therapeutic Drug Monitoring
Published
2025-04-17
DOI
https://doi.org/10.1097/ftd.0000000000001333
Citations
1
Primary Topic
Pharmacological Effects and Toxicity Studies
Type
article
Field-Weighted Citation Impact
3.49
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article

Massive Lamotrigine Intoxication Refractory to Sodium Bicarbonate Treatment

Isabel Gomila, Jordi Puiguriguer, Miguel Ángel Servera, Bernardino Barceló Martín et al.
1 citations
Therapeutic Drug Monitoring
Pharmacological Effects and Toxicity Studies
3.49
article

Massive Lamotrigine Intoxication Refractory to Sodium Bicarbonate Treatment

Isabel Gomila, Jordi Puiguriguer, Miguel Ángel Servera, Bernardino Barceló Martín, Jaime Ortega, Miguel Ángel Elorza, Catalina González Forteza, Juan Ignacio Brisa
article en
1 citations

Abstract

The use of ILE as a rescue option, in addition to other supportive measures, and therapeutic drug monitoring seem to be a reasonable approach, given the patient's refractory response to sodium bicarbonate. Continued research and reporting of such cases will help expand the evidence base and refine management strategies for severe LTG intoxication.

Therapeutic Drug MonitoringVol. 47(4)
Hospital Son Llatzer (ES), Health Research Institute of the Balearic Islands (ES), Research Institute of Health Sciences (ES), Hospital Universitario Son Espases (ES)
Good health and well-being
Openalex Percentile: Top 11%
Pharmacological Effects and Toxicity Studies
3.49
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