Assessment of early response to neoadjuvant chemotherapy in multi-site high-grade serous ovarian cancer using hyperpolarized-13C MRI
This exploratory study demonstrates the potential of <sup>13</sup>C MRI measurements for assessing early response to neoadjuvant chemotherapy in patients with HGSOC.
Authors
- Stephan Ursprung (ORCID: https://orcid.org/0000-0003-2476-178X)
- Andrew N. Priest (ORCID: https://orcid.org/0000-0002-9771-4290)
- Vlad Bura (ORCID: https://orcid.org/0000-0001-9674-2671)
- Rolf F. Schulte (ORCID: https://orcid.org/0000-0002-1334-1264)
- Lucian Beer (ORCID: https://orcid.org/0000-0003-4388-7580)
- Roido Manavaki (ORCID: https://orcid.org/0000-0002-4384-6626)
- Kevin Michael Brindle (ORCID: https://orcid.org/0000-0003-3883-6287)
- Marika Reinius (ORCID: https://orcid.org/0000-0002-9778-3317)
- Ilse Patterson
- Iosif Mendichovszky (ORCID: https://orcid.org/0000-0002-3777-2827)
- Joo Ern Ang (ORCID: https://orcid.org/0000-0003-2103-996X)
- Surrin S. Deen (ORCID: https://orcid.org/0000-0002-6206-7337)
- Luigi Aloj (ORCID: https://orcid.org/0000-0002-7452-4961)
- Mary A. McLean (ORCID: https://orcid.org/0000-0002-3752-0179)
- Mercedes Jimenez-Linan (ORCID: https://orcid.org/0009-0001-0265-9322)
- Kamal Kishore (ORCID: https://orcid.org/0000-0002-4650-8745)
- Carolin M. Sauer (ORCID: https://orcid.org/0000-0003-2168-6630)
- Johanna Field-Rayner
- James D. Brenton (ORCID: https://orcid.org/0000-0002-5738-6683)
- Fraser Robb (ORCID: https://orcid.org/0000-0002-1625-9709)
- M. Locke (ORCID: https://orcid.org/0000-0003-3481-2691)
- Joshua Kaggie (ORCID: https://orcid.org/0000-0001-6706-3442)
- Iris Allajbeu
- Andrew B. Gill (ORCID: https://orcid.org/0000-0002-9287-9563)
- Leonardo Rundo (ORCID: https://orcid.org/0000-0003-3341-5483)
- Ramona Woitek (ORCID: https://orcid.org/0000-0002-9146-9159)
- Dominique‐Laurent Couturier (ORCID: https://orcid.org/0000-0001-5774-5036)
- Clive S. D’Santos (ORCID: https://orcid.org/0000-0003-4592-0487)
- Evis Sala
- Martin J. Graves
- Ferdia A. Gallagher
- Amy Frary
- Valar Franklin
- Gabriel Funingana
Institutions
- Università Cattolica del Sacro Cuore (IT)
- Danube Private University (AT)
- Austrian Research Institute for Artificial Intelligence (AT)
- General Electric (Spain) (ES)
- University of Cambridge (GB)
- Clinical Emergency Hospital Bucharest (RO)
- Cancer Research UK (GB)
- Cambridge University Hospitals NHS Foundation Trust (GB)
- Agostino Gemelli University Polyclinic (IT)
- Cancer Research UK Cambridge Center (GB)
- Hutchison/MRC Research Centre (GB)
- Siemens Healthineers (Germany) (DE)
- Addenbrooke's Hospital (GB)
- Medical University of Vienna (AT)
Publication Details
- Journal
- EJNMMI Research
- Published
- 2025-04-17
- DOI
- https://doi.org/10.1186/s13550-025-01219-5
- Citations
- 1
- Primary Topic
- Advanced NMR Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.76
Funders
- Cancer Research UK
- National Institute for Health and Care Research
- Department of Health and Social Care
- University of Cambridge
- Cambridge University Hospitals
- NIHR Cambridge Biomedical Research Centre
- Cancer Research UK Cambridge Institute, University of Cambridge