Corneal Sensory Changes and Nerve Plexus Abnormalities in Chronic Neuropathic Ocular Pain and Dry Eye Postrefractive Surgery
Persistent high corneal tactile sensitivity postanesthesia, reduced nerve density, and increased microneuroma density in the central cornea may serve as diagnostic indicators for confirming NOP in patients experiencing chronic DE post-LASIK. These findings underscore the potential utility of incorporating these measures into clinical assessments to improve diagnostic accuracy and guide management strategies in this patient population.
Authors
- Amalia Enríquez‐de‐Salamanca (ORCID: https://orcid.org/0000-0003-1274-7796)
- María J. González‐García (ORCID: https://orcid.org/0000-0003-3673-0585)
- Enrique Ortega (ORCID: https://orcid.org/0000-0002-9067-4337)
- Marta Blanco‐Vázquez (ORCID: https://orcid.org/0000-0001-7054-3287)
- Elena Martínez‐Plaza (ORCID: https://orcid.org/0000-0003-3765-2478)
- Alberto López‐Miguel (ORCID: https://orcid.org/0000-0001-9429-1571)
- Amanda Vázquez (ORCID: https://orcid.org/0000-0003-1926-0083)
- Eva M. Sobas (ORCID: https://orcid.org/0000-0002-2712-8616)
- Margarita Calonge (ORCID: https://orcid.org/0000-0001-8178-4836)
Institutions
- Universidad de Valladolid (ES)
- Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (ES)
Publication Details
- Journal
- American Journal of Ophthalmology
- Published
- 2025-04-17
- DOI
- https://doi.org/10.1016/j.ajo.2025.04.004
- Citations
- 7
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 13.15
Funders
- Ministerio de Ciencia, Innovación y Universidades