Simvastatin mitigates ventilator-induced lung injury in mice with acute respiratory distress syndrome via a mechanism partly dependent on neutrophil extracellular traps
Simvastatin attenuated VILI in mice with ARDS, potentially via reductions in neutrophil extracellular traps (NETs) generation and apoptosis.
Authors
- Chao Ma (ORCID: https://orcid.org/0000-0002-2473-387X)
- Weiwei Qin (ORCID: https://orcid.org/0000-0002-4356-6368)
- Wei Han (ORCID: https://orcid.org/0000-0001-8352-7040)
- Xueting Wang (ORCID: https://orcid.org/0000-0001-6141-3077)
- Lixin Sun (ORCID: https://orcid.org/0000-0002-8754-3176)
Institutions
- Qingdao University (CN)
- Shandong University of Aeronautics (CN)
- Qingdao Municipal Hospital (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-04-17
- DOI
- https://doi.org/10.1186/s40001-025-02544-0
- Citations
- 2
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.59