Melkersson–Rosenthal syndrome. A diagnostic dilemma

Melkerrson-Rosenthal syndrome is a disease with a triad of clinical features: unilateral facial palsy; orofacial swelling; and a fissured tongue. It is a subset of orofacial granulomatosis. The authors present a case report to increase awareness of the syndrome among general dental practitioners, who may be the first to encounter its manifestations. The management and outcomes of this case are discussed. National and international guidance is lacking owing to the rarity of the condition. CPD/Clinical Relevance: Early recognition of manifestations of the syndrome is important for timely diagnosis, appropriate referral, and multidisciplinary management to prevent complications.

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Publication Details

Journal
Dental Update
Published
2025-04-02
DOI
https://doi.org/10.12968/denu.2025.52.4.282
Primary Topic
Autoimmune Bullous Skin Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Melkersson–Rosenthal syndrome. A diagnostic dilemma

Mohammed Awad, Amit Dattani, Pengleang Cheang, Sandeth Phan
Dental Update
Autoimmune Bullous Skin Diseases
article

Melkersson–Rosenthal syndrome. A diagnostic dilemma

Mohammed Awad, Amit Dattani, Pengleang Cheang, Sandeth Phan
article en

Abstract

Melkerrson-Rosenthal syndrome is a disease with a triad of clinical features: unilateral facial palsy; orofacial swelling; and a fissured tongue. It is a subset of orofacial granulomatosis. The authors present a case report to increase awareness of the syndrome among general dental practitioners, who may be the first to encounter its manifestations. The management and outcomes of this case are discussed. National and international guidance is lacking owing to the rarity of the condition. CPD/Clinical Relevance: Early recognition of manifestations of the syndrome is important for timely diagnosis, appropriate referral, and multidisciplinary management to prevent complications.

Dental UpdateVol. 52(4)
Royal Stoke University Hospital (GB), Shrewsbury and Telford Hospital NHS Trust (GB)
Openalex Percentile: Top 89%
Autoimmune Bullous Skin Diseases
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