Advancements in Understanding Neurogenesis in Alzheimer's Disease: Current Research and Insights
Alzheimer's disease (AD) is increasingly impacting the aging global population, with its prevalence and mortality rates rising steadily. This trend severely affects the quality of life and intensifies the economic strain on both families and society. Despite ongoing research, effective treatments remain elusive. However, enhancing neurogenesis in the hippocampal dentate gyrus (DG) to promote the formation of new neurons and replace those lost in AD patients' hippocampus holds promise as a potential strategy to improve cognitive and memory functions, offering hope for delaying or even treating the disease.
Authors
- Chenlu Zhu (ORCID: https://orcid.org/0000-0001-7648-6893)
Institutions
- Shandong First Medical University (CN)
Publication Details
- Journal
- Brain Conflux
- Published
- 2025-03-30
- DOI
- https://doi.org/10.71321/4gjht115
- Primary Topic
- Neurogenesis and neuroplasticity mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00