Health-related quality of life and economic impacts in adults with transfusion-dependent β-thalassemia: findings from a prospective longitudinal real-world study
Participants reported substantial humanistic and economic burdens associated with living with TDT. Our findings highlight the need for alternative treatment options that contribute to improvements in HRQoL and reduce economic burden in this patient population.
Authors
- Jennifer Drahos (ORCID: https://orcid.org/0000-0002-8454-9863)
- Nanxin Li (ORCID: https://orcid.org/0009-0006-4412-0997)
- Adriana Boateng-Kuffour
- Farrukh Shah (ORCID: https://orcid.org/0000-0001-5975-1309)
- Zahra Pakbaz
- Antony P. Martin (ORCID: https://orcid.org/0000-0003-4383-6038)
- Melanie Calvert (ORCID: https://orcid.org/0000-0002-1856-837X)
- Neelam Dongha
- Nick Ainsworth
- Laurice Levine
Institutions
- NHS Blood and Transplant (GB)
- University of California, Irvine (US)
- Independent Sector (US)
- Film Independent (US)
- Cellular Therapeutics (United Kingdom) (GB)
- NIHR Research Delivery Network (GB)
- NIHR Birmingham Biomedical Research Centre (GB)
- Oldham Council (GB)
- Vertex Pharmaceuticals (United States) (US)
- University of Birmingham (GB)
Publication Details
- Journal
- Quality of Life Research
- Published
- 2025-04-17
- DOI
- https://doi.org/10.1007/s11136-025-03961-8
- Citations
- 3
- Primary Topic
- Hemoglobinopathies and Related Disorders
- Type
- article
- Field-Weighted Citation Impact
- 4.88
Funders
- Vertex Pharmaceuticals