Reduced insulin use and diabetes complications upon introduction of SGLT-2 inhibitors and GLP1-receptor agonists in low- and middle-income countries: A microsimulation
The introduction of GLP-1 receptor agonists and SGLT-2 inhibitors for managing type 2 diabetes in LMICs could significantly reduce insulin dosage and associated health risks, leading to improved outcomes and reduced disability. These findings suggest that expanding access to these newer diabetes medications in LMICs could have substantial public health benefits.
Publication Details
- Journal
- PLoS Medicine
- Published
- 2025-04-17
- DOI
- https://doi.org/10.1371/journal.pmed.1004559
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Emory University
- Harvard T.H. Chan School of Public Health
- Department of Global Health and Population, Harvard T.H. Chan School of Public Health