Reduced insulin use and diabetes complications upon introduction of SGLT-2 inhibitors and GLP1-receptor agonists in low- and middle-income countries: A microsimulation

The introduction of GLP-1 receptor agonists and SGLT-2 inhibitors for managing type 2 diabetes in LMICs could significantly reduce insulin dosage and associated health risks, leading to improved outcomes and reduced disability. These findings suggest that expanding access to these newer diabetes medications in LMICs could have substantial public health benefits.

Publication Details

Journal
PLoS Medicine
Published
2025-04-17
DOI
https://doi.org/10.1371/journal.pmed.1004559
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00

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article

Reduced insulin use and diabetes complications upon introduction of SGLT-2 inhibitors and GLP1-receptor agonists in low- and middle-income countries: A microsimulation

PLoS Medicine
Diabetes Treatment and Management
article

Reduced insulin use and diabetes complications upon introduction of SGLT-2 inhibitors and GLP1-receptor agonists in low- and middle-income countries: A microsimulation

article en

Abstract

The introduction of GLP-1 receptor agonists and SGLT-2 inhibitors for managing type 2 diabetes in LMICs could significantly reduce insulin dosage and associated health risks, leading to improved outcomes and reduced disability. These findings suggest that expanding access to these newer diabetes medications in LMICs could have substantial public health benefits.

PLoS MedicineVol. 22(4)
Emory University, Harvard T.H. Chan School of Public Health, Department of Global Health and Population, Harvard T.H. Chan School of Public Health
No poverty
Openalex Percentile: Top 90%
Diabetes Treatment and Management
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Reduced insulin use and diabetes complications upon introduction of SGLT-2 inhibitors and GLP1-receptor agonists in low- and middle-income countries: A microsimulation · PLoS Medicine (2025) | TGRS Research Map | TGRS