Onset of chronic pain triggered by a lifestyle-change-based weight loss and exercise regimen

Exercise and weight loss are commonly recommended to patients with chronic pain; these interventions can relieve extra stress on the joints, reduce the perception of pain and combat comorbidities such as obesity, anxiety and depression. However, exercise can also exacerbate existing pain, presenting challenges for adherence to exercise and weight loss regimens. Here, we summarise the unique case of a patient who presented with chronic pain that developed during a natural weight loss regimen. The patient sought assessment due to diffuse pain that commenced after significant weight loss and was exacerbated with continued adherence to lifestyle modifications. He received a diagnosis of fibromyalgia and is currently being treated with nerve blocks and local anaesthetic injections of trigger points. This case of onset of fibromyalgia and chronic pain following lifestyle changes and weight loss underscores the need for further research aiming to understand the complex relationship between exercise, weight loss and chronic pain.

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Publication Details

Journal
BMJ Case Reports
Published
2025-04-01
DOI
https://doi.org/10.1136/bcr-2024-263172
Primary Topic
Fibromyalgia and Chronic Fatigue Syndrome Research
Type
article
Field-Weighted Citation Impact
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article

Onset of chronic pain triggered by a lifestyle-change-based weight loss and exercise regimen

Lily Dawn Hopkinson, Samira Jafari, Elvin Frempong, Saman Zarghom
BMJ Case Reports
Fibromyalgia and Chronic Fatigue Syndrome Research
article

Onset of chronic pain triggered by a lifestyle-change-based weight loss and exercise regimen

Lily Dawn Hopkinson, Samira Jafari, Elvin Frempong, Saman Zarghom
article en

Abstract

Exercise and weight loss are commonly recommended to patients with chronic pain; these interventions can relieve extra stress on the joints, reduce the perception of pain and combat comorbidities such as obesity, anxiety and depression. However, exercise can also exacerbate existing pain, presenting challenges for adherence to exercise and weight loss regimens. Here, we summarise the unique case of a patient who presented with chronic pain that developed during a natural weight loss regimen. The patient sought assessment due to diffuse pain that commenced after significant weight loss and was exacerbated with continued adherence to lifestyle modifications. He received a diagnosis of fibromyalgia and is currently being treated with nerve blocks and local anaesthetic injections of trigger points. This case of onset of fibromyalgia and chronic pain following lifestyle changes and weight loss underscores the need for further research aiming to understand the complex relationship between exercise, weight loss and chronic pain.

BMJ Case ReportsVol. 18(4)
University of Toronto (CA), Society of Interventional Radiology (US), Medical Advanced Pain Specialists (US), University of Guelph (CA)
Good health and well-being
Openalex Percentile: Top 90%
Fibromyalgia and Chronic Fatigue Syndrome Research
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Onset of chronic pain triggered by a lifestyle-change-based weight loss and exercise regimen — Lily Dawn Hopkinson, Samira Jafari, et al. · BMJ Case Reports (2025) | TGRS Research Map | TGRS