Is it possible to separate the testicular and ovarian components of an ovotestis?
Based on the histologic evaluation of the entire ovotestis as well as ovotestis biopsy specimens it does not appear possible to surgically separate the testicular and ovarian component. We have reservations with the concept in both mixed and bipolar ovotestis that it is possible to surgically preserve either the ovarian or testicular component without leaving incongruent tissue. The clinical implications of leaving gonadal tissue inconsistent with the patient's gender identity remains unknown.
Authors
- Linda A. Baker (ORCID: https://orcid.org/0000-0001-8272-4886)
- Christopher S. Cooper (ORCID: https://orcid.org/0000-0002-4169-2088)
- Laurence S. Baskin (ORCID: https://orcid.org/0009-0004-8263-3975)
- Gerald R. Cunha (ORCID: https://orcid.org/0000-0003-2361-370X)
- Yi Li (ORCID: https://orcid.org/0000-0002-2101-0051)
- Mei Cao
Institutions
- University of Iowa (US)
- University of California, San Francisco (US)
- Iowa City Public Library (US)
- Nationwide Mutual Insurance Company (United States) (US)
Publication Details
- Journal
- Journal of Pediatric Urology
- Published
- 2025-04-17
- DOI
- https://doi.org/10.1016/j.jpurol.2025.04.009
- Citations
- 1
- Primary Topic
- Sexual Differentiation and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.81