Risk of False Acetylcholine Receptor Autoantibody Positivity by Radioimmunoprecipitation Assay in Clinical Practice
False AChR-IgG positivity may occur in clinical practice with RIPA and associates with low antibody titer. Caution is needed when titers between 0.5 and 0.9 nmol/L are detected in low-probability situations because failure to recognize false antibody positivity may lead to misdiagnosis and inappropriate treatments.
Authors
- Mariangela Valentina Puci (ORCID: https://orcid.org/0000-0001-5656-6845)
- Pietro Zara (ORCID: https://orcid.org/0000-0002-3521-8320)
- Paola Chessa
- Paolo Solla (ORCID: https://orcid.org/0000-0002-2982-0665)
- Valentina Damato (ORCID: https://orcid.org/0000-0003-1740-4522)
- Giovanni Sotgiu (ORCID: https://orcid.org/0000-0002-1600-4474)
- Elia Sechi (ORCID: https://orcid.org/0000-0003-4698-663X)
- Giovanni Deiana (ORCID: https://orcid.org/0009-0000-6148-3972)
- Antonella M. Morette
Institutions
- University of Sassari (IT)
- University of Cagliari (IT)
- University of Florence (IT)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-17
- DOI
- https://doi.org/10.1212/wnl.0000000000213498
- Citations
- 6
- Primary Topic
- Myasthenia Gravis and Thymoma
- Type
- article
- Field-Weighted Citation Impact
- 8.34