High-fat diet alters retinal lipid composition and gene expression networks in mice
Taken together, by multi-omics studies, we unveiled that HFD leading to the development of retinal diseases may be regulated by alternative pathways of bile acid synthesis, and our study will shed light on the treatment of these diseases.
Authors
- Wenhui Mo (ORCID: https://orcid.org/0000-0003-4766-9345)
- Tianyu Chen (ORCID: https://orcid.org/0000-0002-7616-0874)
- Lin Zhang (ORCID: https://orcid.org/0000-0003-2298-500X)
- Xianjun Zhu (ORCID: https://orcid.org/0000-0002-2531-7552)
- Qian Hao
- Rong Zou
- Jinrui Cai
Institutions
- University of Electronic Science and Technology of China (CN)
- Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (CN)
- Qinghai Tibetan Hospital (CN)
- Henan Provincial People's Hospital (CN)
- Henan Provincial Eye Hospital (CN)
Publication Details
- Journal
- BMC Biology
- Published
- 2025-04-17
- DOI
- https://doi.org/10.1186/s12915-025-02212-z
- Citations
- 2
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 2.33
Funders
- National Natural Science Foundation of China
- Department of Science and Technology of Sichuan Province