Efficacy and safety of direct oral anticoagulants compared with warfarin in antiphospholipid syndrome. Results of a multicenter retrospective cohort study

This study demonstrated comparable efficacy and improved safety of DOACs over warfarin in a predominantly lower-risk APS population. Caution is advised, particularly in APS patients with triple-positive antiphospholipid antibodies or history of arterial thrombosis.

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Publication Details

Journal
Research and Practice in Thrombosis and Haemostasis
Published
2025-04-17
DOI
https://doi.org/10.1016/j.rpth.2025.102856
Primary Topic
Systemic Lupus Erythematosus Research
Type
article
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article

Efficacy and safety of direct oral anticoagulants compared with warfarin in antiphospholipid syndrome. Results of a multicenter retrospective cohort study

Ali Eshaghpour, Mohamed Amgad, Maha AT Elsebaie, Zoe Alexandra Wickham et al.
Research and Practice in Thrombosis and Haemostasis
Systemic Lupus Erythematosus Research
article

Efficacy and safety of direct oral anticoagulants compared with warfarin in antiphospholipid syndrome. Results of a multicenter retrospective cohort study

Ali Eshaghpour, Mohamed Amgad, Maha AT Elsebaie, Zoe Alexandra Wickham, Stephanie Debragga, Manila Gaddh, Stacey A. Fedewa, Jane Jungyoon Park, Juan Li, Allen Li, Mark Crowther
article en

Abstract

This study demonstrated comparable efficacy and improved safety of DOACs over warfarin in a predominantly lower-risk APS population. Caution is advised, particularly in APS patients with triple-positive antiphospholipid antibodies or history of arterial thrombosis.

Research and Practice in Thrombosis and HaemostasisVol. 9(4)
Northwestern University (US), American Cancer Society (US), Emory University (US), University of Ottawa (CA), Ottawa Hospital (CA), University of Chicago Medical Center (US), Ottawa Hospital Research Institute (CA), Imperial College London (GB), McMaster University (CA)
Good health and well-being
Openalex Percentile: Top 88%
Systemic Lupus Erythematosus Research
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Efficacy and safety of direct oral anticoagulants compared with warfarin in antiphospholipid syndrome. Results of a multicenter retrospective cohort study — Ali Eshaghpour, Mohamed Amgad, et al. · Research and Practice in Thrombosis and Haemostasis (2025) | TGRS Research Map | TGRS