Variations in Creatinine Generation Among Patients With Glomerular Disease: Evidence From the NEPTUNE and CureGN Studies
crG was highly dynamic within individuals over time and varied with glomerular disease activity and treatments. The impact of <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mo>Δ</mml:mo></mml:mrow> </mml:math> crG on <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mo>Δ</mml:mo></mml:mrow> </mml:math> Scr -and subsequently on estimation of kidney function-is potentially large. Accounting for these changes or development of alternative kidney function measures are needed among glomerular disease patients.
Authors
- Shalini S. Ramachandra (ORCID: https://orcid.org/0000-0002-8402-184X)
- Jarcy Zee (ORCID: https://orcid.org/0000-0003-0586-1160)
- Dorey A. Glenn (ORCID: https://orcid.org/0000-0003-2796-3037)
- Michael Arbit
- Melody Chiang
- Laura Mariani (ORCID: https://orcid.org/0000-0002-4305-9884)
Institutions
- University of North Carolina at Chapel Hill (US)
- Children's Hospital of Philadelphia (US)
- University of Michigan (US)
- Michigan Medicine (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Kidney Medicine
- Published
- 2025-04-17
- DOI
- https://doi.org/10.1016/j.xkme.2025.101010
- Primary Topic
- Dialysis and Renal Disease Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute of Allergy and Infectious Diseases
- National Institute of Diabetes and Digestive and Kidney Diseases