Design of a 40 MeV superconducting electron linear accelerator for medical isotope production

Abstract As the demand for radiopharmaceuticals steadily increases, the importance of ensuring a stable production and supply of medical isotopes has become more critical than ever. Previous studies have explored methods for producing medical isotopes using electron linear accelerators. The accelerators used in medical isotope production are progressively requiring higher-power electron beam. This paper presents the design of a compact superconducting radio frequency accelerator delivering beam with an average current of 10 mA and an energy of 40 MeV for medical isotope production. The accelerator employs a niobium-tin superconducting radio-frequency cavity to achieve high average beam power and utilizes a conduction-cooling technique at 4 K by a cryocooler for efficient operation. The study primarily focuses on beam dynamics simulations based on 1.3 GHz 2-cell TESLA type cavities. Beam parameter optimization is performed using a Multi-Objective Genetic Algorithm in conjunction with PARMELA and ASTRA simulations. Preliminary engineering analysis indicates that the proposed design offers a promising alternative solution for medical isotope production.

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Publication Details

Journal
Journal of Instrumentation
Published
2025-04-01
DOI
https://doi.org/10.1088/1748-0221/20/04/t04005
Citations
4
Primary Topic
Particle accelerators and beam dynamics
Type
article
Field-Weighted Citation Impact
19.97
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article

Design of a 40 MeV superconducting electron linear accelerator for medical isotope production

K.M. Chen, Haixiao Deng, Duan Gu, Hong-Tao Hou et al.
4 citations
Journal of Instrumentation
Particle accelerators and beam dynamics
19.97
article

Design of a 40 MeV superconducting electron linear accelerator for medical isotope production

K.M. Chen, Haixiao Deng, Duan Gu, Hong-Tao Hou, Zipeng Liu
article en
4 citations

Abstract

Abstract As the demand for radiopharmaceuticals steadily increases, the importance of ensuring a stable production and supply of medical isotopes has become more critical than ever. Previous studies have explored methods for producing medical isotopes using electron linear accelerators. The accelerators used in medical isotope production are progressively requiring higher-power electron beam. This paper presents the design of a compact superconducting radio frequency accelerator delivering beam with an average current of 10 mA and an energy of 40 MeV for medical isotope production. The accelerator employs a niobium-tin superconducting radio-frequency cavity to achieve high average beam power and utilizes a conduction-cooling technique at 4 K by a cryocooler for efficient operation. The study primarily focuses on beam dynamics simulations based on 1.3 GHz 2-cell TESLA type cavities. Beam parameter optimization is performed using a Multi-Objective Genetic Algorithm in conjunction with PARMELA and ASTRA simulations. Preliminary engineering analysis indicates that the proposed design offers a promising alternative solution for medical isotope production.

Journal of InstrumentationVol. 20(04)
Chinese Academy of Sciences (CN), ShanghaiTech University (CN), Shanghai Advanced Research Institute (CN), Shanghai Zhangjiang Laboratory (CN)
Openalex Percentile: Top 1%
Particle accelerators and beam dynamics
19.97
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Design of a 40 MeV superconducting electron linear accelerator for medical isotope production — K.M. Chen, Haixiao Deng, et al. · Journal of Instrumentation (2025) | TGRS Research Map | TGRS