Application of Metagenomic Long-Read Sequencing for the Diagnosis of Herpetic Uveitis
For the detection of etiologic herpes virus DNA fragments, NMA revealed a reasonable sensitivity and high specificity. Our study highlights the potential of nanopore sequencing to facilitate further advances in uveitis diagnosis.
Authors
- Ai Fujita Sajiki (ORCID: https://orcid.org/0000-0001-7474-9194)
- Koji M. Nishiguchi (ORCID: https://orcid.org/0000-0001-5987-4421)
- Kenichi Kawano (ORCID: https://orcid.org/0000-0002-6463-9650)
- Hiroaki Ushida
- Hiroshi Gotô (ORCID: https://orcid.org/0000-0002-6462-9524)
- Kazuhisa Yamada (ORCID: https://orcid.org/0000-0003-0787-4328)
- Kosuke Fujita (ORCID: https://orcid.org/0000-0001-7277-5209)
- Shu Kachi
- Hiroki Kaneko (ORCID: https://orcid.org/0000-0003-0731-6465)
- Daishi Okuda
- Ayana Suzumura (ORCID: https://orcid.org/0000-0001-5013-8604)
- Masaaki Kosaka
- Kenya Yuki (ORCID: https://orcid.org/0000-0001-6180-9370)
- Yoshito Koyanagi (ORCID: https://orcid.org/0000-0001-5559-6305)
- Hiroyuki Komatsu (ORCID: https://orcid.org/0000-0002-8192-3143)
- Yoshihiko Usui (ORCID: https://orcid.org/0000-0002-1258-3587)
- Hideyuki Shimizu (ORCID: https://orcid.org/0000-0002-1349-9483)
Institutions
- Tokyo Medical University (JP)
- Miyake Eye Hospital (JP)
- Yokkaichi Municipal Hospital (JP)
- Nagoya University (JP)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-04-17
- DOI
- https://doi.org/10.1167/iovs.66.4.50
- Citations
- 3
- Primary Topic
- Cytomegalovirus and herpesvirus research
- Type
- article
- Field-Weighted Citation Impact
- 4.06
Funders
- Japan Society for the Promotion of Science