Brain Resting-state Functional Connectivity Mediates the Age-associated Decline in Physical Activity Engagement
Physical activity engagement begins to decrease in middle-age, while functional connectivity between key regions related to inhibitory control and behavior regulation is a potential neural mechanism underlying this age-related decline. These findings provide neurobiological evidence for the hypothesis that aspects of executive function support PA engagement. Moreover, it also identifies potential neural targets for future PA promotion interventions.
Authors
- Arthur Kramer (ORCID: https://orcid.org/0000-0002-1991-5046)
- Meishan Ai (ORCID: https://orcid.org/0000-0003-2676-2962)
- Charles H Hillman
- Emma M. Tinney (ORCID: https://orcid.org/0000-0001-7960-9844)
- Goretti España‐Irla (ORCID: https://orcid.org/0000-0003-2525-6523)
- Tim P. Morris (ORCID: https://orcid.org/0000-0001-5850-3610)
Institutions
- Northeastern University (US)
- Centre for Movement Disorders (CA)
Publication Details
- Journal
- The Journals of Gerontology Series A
- Published
- 2025-04-17
- DOI
- https://doi.org/10.1093/gerona/glaf075
- Citations
- 2
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.86
Funders
- Directorate for Biological Sciences
- Medical Research Council