Effects of Loteprednol Etabonate and Ketorolac Tromethamine on Intraocular Inflammation and Oxidative Stress After Paracentesis‐Induced Blood‐Aqueous Barrier Breakdown in Cats

LE and KT effectively reduced PGE<sub>2</sub> levels following paracentesis. LE also significantly decreased TP levels, mitigated miosis, and preserved GSH, indicating reduced oxidative stress. Considering that KT also reduced PGE<sub>2</sub> levels, further studies are warranted to determine whether KT might effectively reduce protein influx into the anterior chamber at later time points.

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Publication Details

Journal
Veterinary Ophthalmology
Published
2025-04-17
DOI
https://doi.org/10.1111/vop.70020
Citations
2
Primary Topic
Glaucoma and retinal disorders
Type
article
Field-Weighted Citation Impact
3.41

Funders

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article

Effects of Loteprednol Etabonate and Ketorolac Tromethamine on Intraocular Inflammation and Oxidative Stress After Paracentesis‐Induced Blood‐Aqueous Barrier Breakdown in Cats

Nathália de Assis Pereira, Fábio Dumit Pizzinatto, Bianca Eidt Rodrigues, Tânia Maria de Almeida Alves et al.
2 citations
Veterinary Ophthalmology
Glaucoma and retinal disorders
3.41
article

Effects of Loteprednol Etabonate and Ketorolac Tromethamine on Intraocular Inflammation and Oxidative Stress After Paracentesis‐Induced Blood‐Aqueous Barrier Breakdown in Cats

Nathália de Assis Pereira, Fábio Dumit Pizzinatto, Bianca Eidt Rodrigues, Tânia Maria de Almeida Alves, Alexandre Pinto Ribeiro, Suélem Aparecida de França Lemes, Hanna Rodrigues Miranda, Anderson de Oliveira Souza
article en
2 citations

Abstract

LE and KT effectively reduced PGE<sub>2</sub> levels following paracentesis. LE also significantly decreased TP levels, mitigated miosis, and preserved GSH, indicating reduced oxidative stress. Considering that KT also reduced PGE<sub>2</sub> levels, further studies are warranted to determine whether KT might effectively reduce protein influx into the anterior chamber at later time points.

Veterinary OphthalmologyVol. 29(1)
Universidade Federal de Mato Grosso (BR)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Clean water and sanitation
Openalex Percentile: Top 9%
Glaucoma and retinal disorders
3.41
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