Diagnostic and prognostic performance of serum GPC3 and PIVKA-II in AFP-negative hepatocellular carcinoma and establishment of nomogram prediction models
Serum GPC3 and PIVKA-II demonstrate clinical significance in the timely detection and prognosis assessment of N-HCC. The application of nomogram prediction models based on GPC3 and PIVKA-II stands as an important adjunctive tool for diagnosing and prognosticating N-HCC.
Authors
- Zhaolei Cui (ORCID: https://orcid.org/0000-0002-5543-4952)
- Yepei Huang (ORCID: https://orcid.org/0009-0007-2647-8407)
- Jin‐Ching Lin (ORCID: https://orcid.org/0000-0003-2470-1242)
- Yurong Ma (ORCID: https://orcid.org/0000-0002-2432-5614)
- Zhenzhou Xiao
- Yan Chen (ORCID: https://orcid.org/0000-0003-3516-9546)
- Yingying Lin (ORCID: https://orcid.org/0000-0001-9750-2995)
Institutions
- Fujian Medical University (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
- Fujian Provincial Cancer Hospital (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-04-17
- DOI
- https://doi.org/10.1186/s12885-025-14025-y
- Citations
- 7
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 9.25
Funders
- Fujian Provincial Health Technology Project