Factors associated with detection of oligometastatic recurrence and outcome following definitive (Chemo)radiotherapy for oropharyngeal carcinoma
Nearly one-third of first DM in OPC following initial complete response to (C)RT are oligometastases and most occur within the thorax. Most oligometastases are asymptomatic and more commonly detected following a shorter surveillance scan interval. DM-targeted salvage therapy for oligometastases is associated with longer OS. Prospective studies refining surveillance algorithms to increase detection of oligometastases in asymptomatic high-risk OPC patients are indicated.
Authors
- Jie Su (ORCID: https://orcid.org/0000-0002-8772-8613)
- Andrew Hope (ORCID: https://orcid.org/0000-0001-6793-2863)
- David Goldstein (ORCID: https://orcid.org/0000-0001-6142-3291)
- Tong Li (ORCID: https://orcid.org/0000-0003-1525-8971)
- Ezra Hahn (ORCID: https://orcid.org/0000-0002-3206-1903)
- John Waldron (ORCID: https://orcid.org/0000-0002-1050-7329)
- Brian O’Sullivan (ORCID: https://orcid.org/0000-0001-8887-843X)
- Revadhi Chelvarajah
- Scott Victor Bratman (ORCID: https://orcid.org/0000-0001-8610-4908)
- Christopher M. K. L. Yao (ORCID: https://orcid.org/0000-0003-0346-716X)
- Andrew McPartlin (ORCID: https://orcid.org/0000-0001-6746-4852)
- C. Jillian Tsai (ORCID: https://orcid.org/0009-0004-8051-0787)
- Anna Spreafico (ORCID: https://orcid.org/0000-0002-3034-3042)
- Ye Liu (ORCID: https://orcid.org/0000-0003-1922-0196)
- Shao Hui Huang (ORCID: https://orcid.org/0000-0002-8072-4388)
- Jolie Ringash (ORCID: https://orcid.org/0000-0002-7151-2383)
- John Cho (ORCID: https://orcid.org/0000-0003-4531-3396)
- John Kim (ORCID: https://orcid.org/0000-0002-9223-7640)
- Ali Hosni Abdalaty
- Enrique Sanz Garcia
Institutions
- Mount Sinai Hospital (CA)
- Princess Margaret Cancer Centre (CA)
Publication Details
- Journal
- Oral Oncology
- Published
- 2025-04-17
- DOI
- https://doi.org/10.1016/j.oraloncology.2025.107310
- Citations
- 1
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.85