Distinct patterns of cognitive traits in extreme old age and Alzheimer's disease
Cognitive phenotypes in centenarians differ from those in the AD groups Clinical trait to follow consecutive instructions is retained in centenarians but not in AD groups GWAS identified SNPs related to the maintained trait of MMSE in centenarians.
Authors
- Norikazu Hara (ORCID: https://orcid.org/0000-0001-8525-3469)
- Yoko Eguchi (ORCID: https://orcid.org/0000-0003-2215-314X)
- Masaru Mimura (ORCID: https://orcid.org/0000-0002-3874-5273)
- Hideyuki Okano (ORCID: https://orcid.org/0000-0001-7482-5935)
- Takeshi Ikeuchi
- Nobuyoshi Hirose
- Yasumichi Arai (ORCID: https://orcid.org/0000-0003-1746-965X)
- Yoshinori Nishimoto
- Daisuke Ito (ORCID: https://orcid.org/0000-0002-4740-1675)
- Akinori Miyashita (ORCID: https://orcid.org/0000-0003-2508-9649)
- Mika Konishi (ORCID: https://orcid.org/0009-0007-7248-1893)
- Takashi Sasaki
- Yukiko Abe
Institutions
- Keio University (JP)
- Keio University Shonan Fujisawa (JP)
- Niigata University (JP)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1002/alz.70155
- Citations
- 2
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 2.94
Funders
- Japan Agency for Medical Research and Development
- Kanagawa Institute of Industrial Science and Technology
- Keio University
- Eisai
- Japan Society for the Promotion of Science
- Japan Science and Technology Agency
- Research Complex Program