The mechanism of dexmedetomidine regulation of the HIF-1α/FUNDC1 axis in myocardial ischemia/reperfusion injury.

Dex promoted mitophagy by up-regulating HIF-1α to facilitate the transcriptional expression of FUNDC1, thereby ameliorating myocardial injury in MIRI rats.

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Publication Details

Journal
PubMed
Published
2025-12-01
DOI
https://doi.org/10.14670/hh-18-914
Primary Topic
Cancer, Hypoxia, and Metabolism
Type
article
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0.00
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article

The mechanism of dexmedetomidine regulation of the HIF-1α/FUNDC1 axis in myocardial ischemia/reperfusion injury.

Zhenfei Hu, Yidan Huang
PubMed
Cancer, Hypoxia, and Metabolism
article

The mechanism of dexmedetomidine regulation of the HIF-1α/FUNDC1 axis in myocardial ischemia/reperfusion injury.

Zhenfei Hu, Yidan Huang
article en

Abstract

Dex promoted mitophagy by up-regulating HIF-1α to facilitate the transcriptional expression of FUNDC1, thereby ameliorating myocardial injury in MIRI rats.

PubMedVol. 40(12)
Xinjiang Medical University (CN), First Affiliated Hospital of Xinjiang Medical University (CN)
Good health and well-being
Openalex Percentile: Top 91%
Cancer, Hypoxia, and Metabolism
DOISourceOpenAlex
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The mechanism of dexmedetomidine regulation of the HIF-1α/FUNDC1 axis in myocardial ischemia/reperfusion injury. — Zhenfei Hu, Yidan Huang · PubMed (2025) | TGRS Research Map | TGRS