Identification of cancerous tissues based on residual neural network

The identification of cancerous tissues remains challenging due to the complexity of experimental methods and low identification accuracy rates. Therefore, this paper proposes a rapid identification method. We introduce a new theoretical transmission method for modeling laser beams transport in cancerous and normal biological tissues. Using this method, laser speckle patterns carrying tissue information are obtained at the light transmission receiving plane. Then, we propose a three-task residual neural network, T-ResNet-18, for identifying speckle images. We simulate the human normal and cancerous prostate tissues, rat normal and cancerous tissues, and normal and abnormal cell suspension as training samples. The results show the identification accuracy exceeding 99%. Additionally, we discuss the impact of varying dataset sizes, training epochs, and tissue thickness on identification accuracy and compare the performance of T-ResNet-18 with ResNet-18, VGG16 and AlexNet, showing that T-ResNet-18 significantly outperforms classic neural networks.

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Publication Details

Journal
Scientific Reports
Published
2025-04-17
DOI
https://doi.org/10.1038/s41598-025-88441-2
Primary Topic
Spectroscopy Techniques in Biomedical and Chemical Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Identification of cancerous tissues based on residual neural network

Yueqiu Jiang, Ying Liu, Hongwei Wang, Xiaoyun Liu et al.
Scientific Reports
Spectroscopy Techniques in Biomedical and Chemical Research
article

Identification of cancerous tissues based on residual neural network

Yueqiu Jiang, Ying Liu, Hongwei Wang, Xiaoyun Liu, Zihao Zhao, Siyu Gao, Tengfei Chai, Yumeihui Jin
article en

Abstract

The identification of cancerous tissues remains challenging due to the complexity of experimental methods and low identification accuracy rates. Therefore, this paper proposes a rapid identification method. We introduce a new theoretical transmission method for modeling laser beams transport in cancerous and normal biological tissues. Using this method, laser speckle patterns carrying tissue information are obtained at the light transmission receiving plane. Then, we propose a three-task residual neural network, T-ResNet-18, for identifying speckle images. We simulate the human normal and cancerous prostate tissues, rat normal and cancerous tissues, and normal and abnormal cell suspension as training samples. The results show the identification accuracy exceeding 99%. Additionally, we discuss the impact of varying dataset sizes, training epochs, and tissue thickness on identification accuracy and compare the performance of T-ResNet-18 with ResNet-18, VGG16 and AlexNet, showing that T-ResNet-18 significantly outperforms classic neural networks.

Scientific ReportsVol. 15(1)
Shenyang Ligong University (CN)
Department of Education of Liaoning Province, Scientific Research Fund of Liaoning Provincial Education Department
Zero hunger
Openalex Percentile: Top 93%
Spectroscopy Techniques in Biomedical and Chemical Research
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Identification of cancerous tissues based on residual neural network — Yueqiu Jiang, Ying Liu, et al. · Scientific Reports (2025) | TGRS Research Map | TGRS