TO DETERMINE THE DIAGNOSTIC ACCURACY OF TRANSCRANIAL ULTRASOUND IN THE DETECTION OF HYPOXIC ISCHEMIC INJURY IN NEONATES KEEPING MAGNETIC RESONANCE IMAGING AS A GOLD STANDARD

Objective: To ascertain the accuracy of transcranial ultrasound diagnosis in the detection of hypoxic ischemic injury in neonates, keeping magnetic resonance imaging as the gold standard. Material & Methods: A cross-sectional study was conducted on 147 Male and female patients with an age range of 1-28 days in the Department of Radiology, Hayatabad Medical Complex, Peshawar, from 28 February 2023 to 28 August 2023 (06 months). The patients were suspected of hypoxic-ischemic injury, i.e., suffered from perinatal asphyxia. The diagnostic accuracy of transcranial sonography in detecting neonatal hypoxic-ischemic injury was determined. Results: The mean age of the patients was 14.44±7.77 days. The accuracy of transcranial ultrasound diagnosis in the detection of hypoxic ischemic injury by taking magnetic resonance imaging as the gold standard was 76.19%, with sensitivity 81.61%, specificity 68.33%, Positive Predictive Value 78.89%, and Negative Predictive Value 71.93%. Conclusion: From our study, we conclude that transcranial ultrasound is an accurate modality in detecting neonatal hypoxic ischemic injury with a diagnostic accuracy of 76.19%, a sensitivity of 81.61%, and a specificity of 68.33%.