Increased rates of [18F]FDG accumulation in the brain in children could lead to a lower amount of [18F]FDG reaching other organs and tumors: Is a new SUV correction factor that considers [18F]FDG uptake of the brain in children necessary?
We showed that the [<sup>18</sup>F]FDG accumulation rate was higher in the brain and lower in the liver in the children when compared to adults. Our findings suggest that increased uptake of [<sup>18</sup>F]FDG in children's brains may lead to reduced activity reaching other organs and tumor tissue. To improve diagnostic accuracy, adapted SUV correction protocols can be developed for pediatric populations, considering age-related changes in [<sup>18</sup>F]FDG uptake ratio of the brain.
Authors
- Ebru Tatçı (ORCID: https://orcid.org/0000-0002-9216-658X)
- Özlem Özmen (ORCID: https://orcid.org/0000-0002-5392-1626)
- Seval Beykan Schuerrle
Institutions
- Memorial Ankara Hospital (TR)
- Furtwangen University (DE)
Publication Details
- Journal
- Revista Española de Medicina Nuclear e Imagen Molecular (English Edition)
- Published
- 2025-04-17
- DOI
- https://doi.org/10.1016/j.remnie.2025.500123
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00