In-silico analysis of CEP55/E2F1/hsa-let-7b-5p/TMPO-AS1 axis-based ceRNA network promoting poor prognosis in lung adenocarcinoma smokers

Smokers with lung adenocarcinoma had worse prognoses due to higher E2F1, CEP55, and TMPO-AS1 levels. Also, TMPO-AS1 sponge formation with hsa-let-7b-5p may be the cause of this feedback loop.

Authors

Rajeev Nema (ORCID: https://orcid.org/0000-0003-1572-0409)
Gurpreet Kaur Bamrah (ORCID: https://orcid.org/0009-0000-3968-2844)
Saurabh Srivastava (ORCID: https://orcid.org/0000-0002-3032-5557)
Prerna Vats (ORCID: https://orcid.org/0009-0005-6359-3186)
Sakshi Nirmal

Institutions

Manipal University Jaipur

Publication Details

Journal: Bioimpacts
Published: 2025-04-16
DOI: https://doi.org/10.34172/bi.30585
Primary Topic: Cancer-related molecular mechanisms research
Type: article
Field-Weighted Citation Impact: 0.00

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article

In-silico analysis of CEP55/E2F1/hsa-let-7b-5p/TMPO-AS1 axis-based ceRNA network promoting poor prognosis in lung adenocarcinoma smokers

Rajeev Nema, Gurpreet Kaur Bamrah, Saurabh Srivastava, Prerna Vats et al.

Apr 16, 2025

Bioimpacts

Cancer-related molecular mechanisms research

article

In-silico analysis of CEP55/E2F1/hsa-let-7b-5p/TMPO-AS1 axis-based ceRNA network promoting poor prognosis in lung adenocarcinoma smokers

Rajeev Nema, Gurpreet Kaur Bamrah, Saurabh Srivastava, Prerna Vats, Sakshi Nirmal

April 16, 2025article en

Abstract

Smokers with lung adenocarcinoma had worse prognoses due to higher E2F1, CEP55, and TMPO-AS1 levels. Also, TMPO-AS1 sponge formation with hsa-let-7b-5p may be the cause of this feedback loop.

BioimpactsVol. 15

Manipal University Jaipur

Good health and well-being

Openalex Percentile: Top 91%

Cancer-related molecular mechanisms research

DOI Open Access PDF OpenAlex

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