Dysregulated maternal and newborn fatty acid, sugar and amino acid metabolism associated with high birth weight
Our findings indicate that altered maternal sugar and energy metabolism, newborn sugar and amino acid metabolism, and newborn C21-steroid hormone biosynthesis were associated with high birth weight. Dysregulated metabolism in pregnant women and newborn may contribute to the pathophysiological mechanisms linking maternal excessive gestational weight gain and multiparity with high birth weight.
Authors
- David V. Conti (ORCID: https://orcid.org/0000-0002-2941-7833)
- Dean P. Jones (ORCID: https://orcid.org/0000-0002-2090-0677)
- Roya Gheissari (ORCID: https://orcid.org/0000-0002-4796-2333)
- Carrie V. Breton (ORCID: https://orcid.org/0000-0002-6082-4066)
- Claire Li (ORCID: https://orcid.org/0009-0007-7968-8715)
- Chenyu Qiu (ORCID: https://orcid.org/0000-0002-1360-0166)
- Theresa M. Bastain (ORCID: https://orcid.org/0000-0002-0029-5641)
- Jiawen Liao (ORCID: https://orcid.org/0000-0001-8246-0542)
- Zhanghua Chen (ORCID: https://orcid.org/0000-0002-6424-6697)
- Anika Kapai
Institutions
- University of Southern California (US)
- Emory University (US)
Publication Details
- Journal
- International Journal of Obesity
- Published
- 2025-04-17
- DOI
- https://doi.org/10.1038/s41366-025-01775-9
- Citations
- 2
- Primary Topic
- Gestational Diabetes Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 4.11
Funders
- Emory University
- National Institute of Environmental Health Sciences