Addressing Cervical Stenosis and Uterine Fibroids in IVF: A Case Study on the Effectiveness of TMET

This case study presents a 38-year-old female with a history of infertility complicated by severe cervical stenosis and intramural fibroids, which rendered traditional transcervical embryo transfer (ET) ineffective. After previously failed cycles of in vitro fertilization, the couple was advised for transmyometrial embryo transfer (TMET), an invasive technique that places the embryo straight into the lining of the endometrium rather than through the cervix. Full assessment showed appropriate hormone levels and normospermia excluding the presence of male factor infertility. The patient received ovarian stimulation, oocyte retrieval, and ET through TMET. After the procedure, progesterone supplementations were given to sustain the luteal phase. A beta hCG test returned a positive result after 2 weeks of the transfer confirming pregnancy. This case illustrates the effectiveness of TMET in avoiding the anatomical issues associated with conventional ET and reinforces the concept of the need for customized fertility care.

Authors

Institutions

Publication Details

Journal
Journal of Pharmacy And Bioallied Sciences
Published
2025-04-17
DOI
https://doi.org/10.4103/jpbs.jpbs_1918_24
Primary Topic
Gynecological conditions and treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Addressing Cervical Stenosis and Uterine Fibroids in IVF: A Case Study on the Effectiveness of TMET

Akash More, Namrata Choudhary, Sudhanshu Dakre, Shradha Ulhe
Journal of Pharmacy And Bioallied Sciences
Gynecological conditions and treatments
article

Addressing Cervical Stenosis and Uterine Fibroids in IVF: A Case Study on the Effectiveness of TMET

Akash More, Namrata Choudhary, Sudhanshu Dakre, Shradha Ulhe
article en

Abstract

This case study presents a 38-year-old female with a history of infertility complicated by severe cervical stenosis and intramural fibroids, which rendered traditional transcervical embryo transfer (ET) ineffective. After previously failed cycles of in vitro fertilization, the couple was advised for transmyometrial embryo transfer (TMET), an invasive technique that places the embryo straight into the lining of the endometrium rather than through the cervix. Full assessment showed appropriate hormone levels and normospermia excluding the presence of male factor infertility. The patient received ovarian stimulation, oocyte retrieval, and ET through TMET. After the procedure, progesterone supplementations were given to sustain the luteal phase. A beta hCG test returned a positive result after 2 weeks of the transfer confirming pregnancy. This case illustrates the effectiveness of TMET in avoiding the anatomical issues associated with conventional ET and reinforces the concept of the need for customized fertility care.

Journal of Pharmacy And Bioallied SciencesVol. 17(Suppl 1)
Datta Meghe Institute of Higher Education and Research (IN)
Openalex Percentile: Top 89%
Gynecological conditions and treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.