Effects of intravenous morphine and lidocaine on bacterial growth
At plasma concentrations, morphine and lidocaine do not directly affect bacterial growth in vitro microbiological laboratory testing. Lidocaine on the other hand, in higher plasma concentrations, disrupts bacterial ultrastructure. Further studies are needed to investigate the significance and clinical impact of these findings.
Authors
- Stanca Lucia Pandrea (ORCID: https://orcid.org/0000-0003-0108-7868)
- L. Matros
- Mirela Flonta (ORCID: https://orcid.org/0000-0001-5478-8815)
- Daniela Ionescu (ORCID: https://orcid.org/0000-0002-2847-537X)
- Cristiana Iulia Osoian
- Adrian Florea
Institutions
- Outcomes Research Consortium (US)
- Iuliu Hațieganu University of Medicine and Pharmacy (RO)
- Research Institute for Analytical Instrumentation (RO)
Publication Details
- Journal
- BMC Anesthesiology
- Published
- 2025-04-17
- DOI
- https://doi.org/10.1186/s12871-025-03070-6
- Citations
- 1
- Primary Topic
- Anesthesia and Neurotoxicity Research
- Type
- article
- Field-Weighted Citation Impact
- 1.32