Differentiation between Nonenhancing Tumor in Glioblastoma and Vasogenic Edema Using Diffusion-Weighted and Dynamic Susceptibility Contrast MR Imaging
Diffusion- and perfusion-weighted MR imaging, particularly ADC and rCBV measurements, provide valuable biomarkers for differentiating nonenhancing glioblastoma from vasogenic edema. The identified threshold values may enhance glioblastoma characterization, improve preoperative differentiation from metastases, and support more precise, image-guided clinical management.
Authors
- Dhairya A. Lakhani (ORCID: https://orcid.org/0000-0001-7577-1887)
- Janet Mei (ORCID: https://orcid.org/0000-0003-4184-8924)
- Sahar Alizada (ORCID: https://orcid.org/0000-0001-5284-414X)
- Hongbo Bao (ORCID: https://orcid.org/0000-0003-1043-6951)
- Haris I. Sair (ORCID: https://orcid.org/0000-0002-5077-0471)
- Vivek Srikar Yedavalli (ORCID: https://orcid.org/0000-0002-2450-4014)
- Yasmin Aly
Institutions
- The University of Texas MD Anderson Cancer Center (US)
- Johns Hopkins Hospital (US)
Publication Details
- Journal
- American Journal of Neuroradiology
- Published
- 2025-04-17
- DOI
- https://doi.org/10.3174/ajnr.a8788
- Primary Topic
- MRI in cancer diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00