Evaluating the Accuracy of Web-Based and In-Clinic Subjective Cognitive Decline Assessments in Detecting Cognitive Impairment: Multicohort Study
Web-based ECog scores, both the full-length and short-form, were as valid as in-clinic ECog scores for identifying clinically diagnosed CI. In addition, Self-ECog12 was as effective as full-length Self-ECog to identify CI in a web-based setting, offering a cost-effective and accessible screening tool for large-scale studies. These results highlight the value of the web-based ECog as a valid tool for identifying older adults with CI in a remote clinical study, facilitating early detection and referral for comprehensive evaluations for identifying potential candidates for disease-modifying therapy.
Authors
- Rachana Tank (ORCID: https://orcid.org/0000-0002-4771-6685)
- Juliet Fockler
- Diana Truran (ORCID: https://orcid.org/0000-0001-7159-2216)
- Miriam T. Ashford (ORCID: https://orcid.org/0000-0003-4045-6435)
- Jae Myeong Kang (ORCID: https://orcid.org/0000-0003-0803-9332)
- R. Scott Mackin (ORCID: https://orcid.org/0000-0001-8072-476X)
- Derek Flenniken
- Manchumad Manjavong (ORCID: https://orcid.org/0000-0002-9334-5571)
- Joseph Eichenbaum (ORCID: https://orcid.org/0000-0003-1841-5936)
- Anna Aaronson (ORCID: https://orcid.org/0000-0002-5231-9684)
- Rachel L. Nosheny (ORCID: https://orcid.org/0000-0003-4995-8319)
- Erika Cavallone
- Bernard Landavazo
- Michael Walter Weiner (ORCID: https://orcid.org/0000-0002-0144-1954)
- Monica R. Camacho
- Adam Diaz
- Sarah Tomaszewski Farias (ORCID: https://orcid.org/0009-0009-8969-3387)
- Melanie J. Miller (ORCID: https://orcid.org/0000-0002-7189-1109)
Institutions
- Gachon University (KR)
- San Francisco VA Medical Center (US)
- Khon Kaen University (TH)
- University of California, San Francisco (US)
- University of California System (US)
- UK Dementia Research Institute (GB)
- Northern California Institute for Research and Education (US)
- University College London (GB)
- University of California, Davis (US)
Publication Details
- Journal
- Journal of Medical Internet Research
- Published
- 2025-04-17
- DOI
- https://doi.org/10.2196/69689
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00