Variability in Response to Valsartan and Its Relationship With <i>AGT M235T</i> Genotype and Other Nongenetic Parameters Among a Sample of Hypertensive Individuals in Jordan: A Prospective Pilot Study
This study identifies the <i>AGT M235T</i> genotype as a potential genetic contributor to variability in the valsartan response. Associations with age, height, and sex underscore the importance of considering genetic and demographic factors in tailoring valsartan therapy, for advancing personalized hypertension management.
Authors
- Khaled Ojjoh (ORCID: https://orcid.org/0000-0003-2018-7522)
- Ayman Wahbeh (ORCID: https://orcid.org/0000-0002-3159-2518)
- Sameeha Alshelleh (ORCID: https://orcid.org/0000-0003-4216-0662)
- Hussam Alhawari (ORCID: https://orcid.org/0000-0003-2525-9193)
- Hussein Alhawari (ORCID: https://orcid.org/0000-0002-5413-3736)
- Yazun Jarrar (ORCID: https://orcid.org/0000-0002-5943-7229)
- Dalia Abdelrazaq
- Malek Zihlif
Institutions
- University of Jordan (JO)
- Al-Balqa Applied University (JO)
Publication Details
- Journal
- Health Science Reports
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1002/hsr2.70611
- Citations
- 4
- Primary Topic
- Renin-Angiotensin System Studies
- Type
- article
- Field-Weighted Citation Impact
- 5.55
Funders
- University of Jordan