GLUT1 inhibition by BAY-876 induces metabolic changes and cell death in human colorectal cancer cells
BAY-876 treatment induced metabolic changes and inhibited cell proliferation in human CRC cell lines. Using BAY-876 is a potential novel approach for treating CRC.
Authors
- Jun Kinoshita (ORCID: https://orcid.org/0000-0003-1673-8272)
- Noriyuki Inaki (ORCID: https://orcid.org/0000-0002-4241-5015)
- Masato Hayashi (ORCID: https://orcid.org/0000-0003-2437-056X)
- Toshikatsu Tsuji (ORCID: https://orcid.org/0000-0002-3430-0568)
- Mariko Tanaka (ORCID: https://orcid.org/0000-0002-6877-9212)
- Daisuke Yamamoto (ORCID: https://orcid.org/0000-0002-2628-7172)
- Akiko Kobayashi (ORCID: https://orcid.org/0000-0001-9396-3401)
- Hiroto Saito (ORCID: https://orcid.org/0000-0002-0920-7062)
- Hideki Moriyama (ORCID: https://orcid.org/0000-0003-0180-7968)
- Shinichi Harada (ORCID: https://orcid.org/0000-0002-1115-7623)
- Keishi Nakamura
Institutions
- Kanazawa University (JP)
- Kanazawa Medical University (JP)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-04-17
- DOI
- https://doi.org/10.1186/s12885-025-14141-9
- Citations
- 15
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 14.04